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PGC-1α deficiency causes spontaneous kidney inflammation

PGC-1α deficiency causes spontaneous kidney inflammation

Abstract

PGC-1α (peroxisome proliferator-activated receptor gamma coactivator-1α, PPARGC1A) regulates the expression of genes involved in energy homeostasis and mitochondrial biogenesis. PGC-1α deficiency has been linked to various diseases, including kidney inflammation. The study aims to investigate the effects of PGC-1α deficiency on kidney function and inflammation. The results of this study will provide valuable insights into the molecular mechanisms underlying kidney inflammation and may lead to the development of novel therapeutic strategies for the treatment of kidney diseases.

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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average