Protein disulfide isomerases are promising targets
Protein disulfide isomerases are promising targets
The present study focused on the expression patterns, prognostic values and potential mechanism of the PDI family in gliomas. Most PDI family members' mRNA expressions were observed significantly different between glioma and normal brain tissues. The study aimed to investigate the role of PDI family in glioma development and progression. The results showed that PDI family members were significantly upregulated in glioma tissues compared to normal brain tissues. The study also found that PDI family members were associated with poor prognosis in glioma patients. The study suggested that PDI family members may serve as potential biomarkers for glioma diagnosis and treatment. Furthermore, the study revealed that PDI family members may play a crucial role in the development and progression of glioma through regulating cell proliferation, apoptosis, and angiogenesis. The study provided new insights into the molecular mechanisms of glioma development and progression, and highlighted the potential of PDI family members as therapeutic targets for glioma treatment.
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