Methyl-dependent and spatial-specific DNA recognition

appsraidkeyboard_double_arrow_right Research Activity 27 Jun 2012

Methyl-dependent and spatial-specific DNA recognition

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Abstract

This research activity focuses on the study of a transcription factor that recognizes two versions of a 7-base pair response element, either 5΄- GAG CA-3΄ or 5΄- GAG CA-3΄ (where M = 5-methylcytosine). The goal is to understand the mechanisms behind this recognition and its implications in gene regulation.

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