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[Advances of the relationship between leptin system and non-small cell lung cancer].

descriptionPublicationkeyboard_double_arrow_right Article 01 Apr 2014Publisher:Chinese Anti-Cancer Association; Chinese Antituberculosis AssociationJournal:Zhongguo fei ai za zhi = Chinese journal of lung cancer, volume 17 (issn: 1999-6187,

Authors: Tengfei Wei; Qian Shen; Longkun Lu; Chaoping Fang;

doi: 10.3779/j.issn.1009-3419.2014.04.10

pmid: 24758911

pmc: PMC6000024

[Advances of the relationship between leptin system and non-small cell lung cancer].

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Abstract

Leptin system plays an important role in lung inflammation and tumorigenesis, but the precise function in the tumormicrovironment and the prognosis value of the leptin system in lung cancer have not been fully elucidated. This review will focus on the relationship between leptin system and non-small cell lung cancer (NSCLC), in which special attentions will be paid on the expression of leption and its receptor (LepR) in peripheral blood and tumor tissues, leptin-related signal transduction pathways, the interaction between leption and regulatory T cells (Treg) and the gene polymorphisms of leptin and leptin receptor, and possibly provide new strategies for diagnosis and treatment of NSCLC.

Related Organizations

Second Military Medical University
China (People's Republic of)
Changhai Hospital
China (People's Republic of)

Keywords

Leptin, Lung Neoplasms, Leptin-receptor, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Gene Expression Regulation, Neoplastic, Lung neoplasms, Carcinoma, Non-Small-Cell Lung, Animals, Humans, Receptors, Leptin, RC254-282, Signal Transduction

12 Research products, page 1 of 2

Leptin
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Leptin
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Leptin
2017IsRelatedTo
Leptin
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Leptin receptor
2017IsRelatedTo
LEPR protein
2017IsRelatedTo
LEPR protein
2017IsRelatedTo
Leptin
2017IsRelatedTo
Leptin
2017IsRelatedTo
Leptin receptor
2017IsRelatedTo

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