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The properties of the multicopy suppressor of the ogd1 mutation in yeast.

Authors: Y, Gbelská; D, Mockovciaková; J, Timko; J, Subík;

The properties of the multicopy suppressor of the ogd1 mutation in yeast.

Abstract

The 8.1 kb chromosomal fragment partially suppressing the ogd1 mutation in Saccharomyces cerevisiae has been cloned. The molecular analysis revealed that its suppressor gene codes for a natural glutamine tRNA(CAG) and maps on chromosome XIII in the upstream region of the URA10 gene. The multicopy plasmids containing this tRNA gene also suppressed the standard trp1-1 amber mutation and conferred the sensitivity of yeast cells to paromomycin and increased temperature.

Related Organizations
Keywords

Glycerol, Paromomycin, Genes, Fungal, Restriction Mapping, Temperature, Chromosome Mapping, Saccharomyces cerevisiae, Protein Biosynthesis, RNA, Transfer, Gln, Mutation, Ketoglutarate Dehydrogenase Complex, Chromosomes, Fungal, Cloning, Molecular, Genes, Suppressor

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Powered by OpenAIRE graph
citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
2
Average
Average
Average