Identification of novel cyclin-dependent kinases interacting with the CKS1 protein of Arabidopsis.
Identification of novel cyclin-dependent kinases interacting with the CKS1 protein of Arabidopsis.
The SUC1/CKS1 proteins interact with cyclin-dependent kinases (CDKs) and play an essential, but yet not entirely resolved, role in the regulation of the cell cycle. With the Arabidopsis thaliana CKS1At protein as bait in a two-hybrid screen, two novel Arabidopsis CDKs, Arath;CDKB1;2 and Arath;CDKB2;1, were isolated. A closely related homologue of Arath;CDKB2;1 was discovered in the databases and was nominated Arath;CDKB2;2. Transcript analysis of the five known Arath;CDKA and Arath;CDKB genes revealed that they all had the highest expression in flowers and cell suspensions. Differences in the expression patterns in roots, leaves and stems suggest unique roles for each CDK.
- Ghent University Belgium
Fungal Proteins, Saccharomyces cerevisiae Proteins, Plant Stems, Arabidopsis Proteins, Gene Expression Regulation, Plant, Cell Cycle, Molecular Sequence Data, Arabidopsis, Cell Cycle Proteins, Cells, Cultured, Cyclin-Dependent Kinases, Adaptor Proteins, Signal Transducing, Plant Proteins
Fungal Proteins, Saccharomyces cerevisiae Proteins, Plant Stems, Arabidopsis Proteins, Gene Expression Regulation, Plant, Cell Cycle, Molecular Sequence Data, Arabidopsis, Cell Cycle Proteins, Cells, Cultured, Cyclin-Dependent Kinases, Adaptor Proteins, Signal Transducing, Plant Proteins
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