HLA-DQB1*05 association with Hashimoto's thyroiditis in children of Northern Greek origin.
Copyright policy )HLA-DQB1*05 association with Hashimoto's thyroiditis in children of Northern Greek origin.
In order to investigate HLA-DRB1 and HLADQB1 gene polymorphisms in Northern Greek pediatric population with Hashimoto's thyroiditis (HT), we analyzed the distribution of these alleles in 17 patients and in 181 healthy subjects using polymerase chain reaction. No significant association was detected between HT and alleles analyzed. However, HLA-DQB1*05 was significantly increased in patients with age of diagnosis > 10 years (87.5%) compared to those with age of diagnosis
Male, Polymorphism, Genetic, Adolescent, Greece, Puberty, HLA-DR Antigens, Hashimoto Disease, Gene Frequency, HLA-DQ Antigens, HLA-DQ beta-Chains, Humans, Female, Genetic Predisposition to Disease, Child, HLA-DRB1 Chains
Male, Polymorphism, Genetic, Adolescent, Greece, Puberty, HLA-DR Antigens, Hashimoto Disease, Gene Frequency, HLA-DQ Antigens, HLA-DQ beta-Chains, Humans, Female, Genetic Predisposition to Disease, Child, HLA-DRB1 Chains
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