Effect of exogenous selenium on the testicular toxicity induced by ethanol in rats.
Effect of exogenous selenium on the testicular toxicity induced by ethanol in rats.
The effects of supplementation of selenium at a dose of 10 microg/ kg body weight were investigated on ethanol induced testicular toxicity in rats. In the present study, four groups of male albino rats were maintained for 60 days, as follows: (1) Control group (normal diet) (2) Ethanol group (4g/kg body weight) (3) Selenium (10 microg/kg body weight) (4) Ethanol + Selenium (4g/kg body weight + 10 microg/kg body weight). Results revealed that ethanol intake caused drastic changes in the sperm count, sperm motility and sperm morphology. It also reduced the levels of testosterone and fructose. The activities of 3betaHSD, 17betaHSD in the testis and SDH in the seminal plasma were also reduced. Lipid peroxidation was also enhanced as the lipid peroxidation products were increased and the activities of the scavenging enzymes were reduced. But on coadministration of selenium along with alcohol all the biochemical parameters were altered to near normal levels indicating a protective effect of selenium. These results were reinforced by the histopathological studies.
- University of Kerala India
Male, 3-Hydroxysteroid Dehydrogenases, 17-Hydroxysteroid Dehydrogenases, Ethanol, Central Nervous System Depressants, Fructose, Spermatozoa, Antioxidants, Rats, Rats, Sprague-Dawley, Selenium, Semen, Testis, Sperm Motility, Animals, Testosterone, Lipid Peroxidation
Male, 3-Hydroxysteroid Dehydrogenases, 17-Hydroxysteroid Dehydrogenases, Ethanol, Central Nervous System Depressants, Fructose, Spermatozoa, Antioxidants, Rats, Rats, Sprague-Dawley, Selenium, Semen, Testis, Sperm Motility, Animals, Testosterone, Lipid Peroxidation
6 Research products, page 1 of 1
- 2017IsRelatedTo
- 2017IsRelatedTo
citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).15 popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.Top 10% influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).Top 10% impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.Average
