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EGF Receptor Signalling: Roles of Star and Rhomboid Revealed

pmid: 11790319
EGF Receptor Signalling: Roles of Star and Rhomboid Revealed
Recent studies have clarified how the active form of the Drosophila EGF receptor ligand Spitz is produced: Star chaperones Spitz in the ER and mediates its transport to the Golgi, where the intramembrane serine protease Rhomboid cleaves the Spitz proprotein to initiate secretion.
- University of Münster Germany
Agricultural and Biological Sciences(all), Epidermal Growth Factor, Biochemistry, Genetics and Molecular Biology(all), Serine Endopeptidases, Membrane Proteins, Models, Biological, ErbB Receptors, Protein Transport, Animals, Drosophila Proteins, Drosophila, Signal Transduction
Agricultural and Biological Sciences(all), Epidermal Growth Factor, Biochemistry, Genetics and Molecular Biology(all), Serine Endopeptidases, Membrane Proteins, Models, Biological, ErbB Receptors, Protein Transport, Animals, Drosophila Proteins, Drosophila, Signal Transduction
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citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).20 popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.Average influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).Top 10% impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.Top 10%