Increased Synaptophysin Expression Through Whisker Stimulation in Rat

Name: Increased Synaptophysin Expression Through Whisker Stimulation in Rat
Creator: Hidetoshi, Ishibashi
Keywords: 0301 basic medicine, Male, Afferent Pathways, Neuronal Plasticity, Presynaptic Terminals, Synaptophysin, Somatosensory Cortex, Synaptic Transmission, Functional Laterality, Rats

descriptionPublicationkeyboard_double_arrow_right Article 01 Apr 2002 English Publisher:Springer Science and Business Media LLCJournal:Cellular and Molecular Neurobiology, volume 22, pages 191-195 (issn: 0272-4340, eissn: 1573-6830,

Authors: Hidetoshi, Ishibashi;

doi: 10.1023/a:1019817906139

pmid: 12363201

Increased Synaptophysin Expression Through Whisker Stimulation in Rat

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Abstract

1. Synaptophysin is responsible for the cycling of the synaptic vesicles containing the neurotransmitter, and it can be phosphorylated. 2. This study examined whether repeated whisker stimulation alters the expression of synaptophysin mRNA in the rat barrel cortex, and found induced expression of synaptophysin mRNA in the contralateral barrel cortex compared to that in the ipsilateral hemi sphere. 3. This result suggests that synaptophysin is involved in the modulation of the synaptic plasticity.

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Institute of Science Tokyo
Japan

Keywords

Male, Afferent Pathways, Neuronal Plasticity, Presynaptic Terminals, Synaptophysin, Somatosensory Cortex, Synaptic Transmission, Functional Laterality, Rats, Up-Regulation, Rats, Sprague-Dawley, Vibrissae, Animals, RNA, Messenger, Mechanoreceptors

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