Cloning of a cDNA encoding a mouse transcriptional repressor displaying striking sequence conservation across vertebrates
Copyright policy )Cloning of a cDNA encoding a mouse transcriptional repressor displaying striking sequence conservation across vertebrates
The nucleotide sequence encoding an approx. 120-kDa transcriptional repressor (MEB1) was determined from a cDNA which was cloned from a mouse brain library. An alignment of the deduced amino-acid sequences of the putative functional domains of MEB1 with those from the human, hamster and chicken homologues reveals a dramatic degree of conservation.
- Howard Hughes Medical Institute United States
- University of Pennsylvania United States
Homeodomain Proteins, Binding Sites, DNA, Complementary, Transcription, Genetic, Molecular Sequence Data, Zinc Finger E-box-Binding Homeobox 1, DNA-Binding Proteins, Repressor Proteins, Mice, Cricetinae, Vertebrates, Animals, Amino Acid Sequence, Cloning, Molecular, Chickens, Conserved Sequence, Phylogeny, Transcription Factors
Homeodomain Proteins, Binding Sites, DNA, Complementary, Transcription, Genetic, Molecular Sequence Data, Zinc Finger E-box-Binding Homeobox 1, DNA-Binding Proteins, Repressor Proteins, Mice, Cricetinae, Vertebrates, Animals, Amino Acid Sequence, Cloning, Molecular, Chickens, Conserved Sequence, Phylogeny, Transcription Factors
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