Playing Chess with HIV
Authors: Andrew B, Ward;
pmid: 30784575
Playing Chess with HIV
Abstract
HIV envelope glycoprotein (Env) exhibits extreme antigenic variation that can be countered by an amazing class of immunoglobulins known as broadly neutralizing antibodies. Dingens et al. (2019) use saturating mutagenesis of Env to play out all of the potential bnAb escape strategies and in doing so define the functional epitopes of these important vaccine and immunotherapeutic targets.
Related Organizations
- Scripps Research Institute United States
Keywords
Epitopes, HIV-1, env Gene Products, Human Immunodeficiency Virus, HIV Antibodies, Antibodies, Neutralizing
Epitopes, HIV-1, env Gene Products, Human Immunodeficiency Virus, HIV Antibodies, Antibodies, Neutralizing
2 Research products, page 1 of 1
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citations
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This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
popularity
Popularity provided by BIP!
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
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