High frequencies of SF3B1 and JAK2 mutations in refractory anemia with ring sideroblasts associated with marked thrombocytosis strengthen the assignment to the category of myelodysplastic/myeloproliferative neoplasms
Copyright policy )High frequencies of SF3B1 and JAK2 mutations in refractory anemia with ring sideroblasts associated with marked thrombocytosis strengthen the assignment to the category of myelodysplastic/myeloproliferative neoplasms
Mutations of spliceosome genes were shown to occur frequently in different entities.[1][1] Remarkably, mutations in SF3B1 (splicing factor 3b, subunit 1) were associated with the morphological feature of ring sideroblasts[1][1]-[3][2] and were also found in refractory anemia with ring sideroblasts
Thrombocytosis, Anemia, Refractory, Janus Kinase 2, Ribonucleoprotein, U2 Small Nuclear, Phosphoproteins, Myelodysplastic-Myeloproliferative Diseases, Mutation, Humans, Diseases of the blood and blood-forming organs, RNA Splicing Factors, RC633-647.5
Thrombocytosis, Anemia, Refractory, Janus Kinase 2, Ribonucleoprotein, U2 Small Nuclear, Phosphoproteins, Myelodysplastic-Myeloproliferative Diseases, Mutation, Humans, Diseases of the blood and blood-forming organs, RNA Splicing Factors, RC633-647.5
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