An miRNA-mediated therapy for SCA6 blocks IRES-driven translation of the CACNA1A second cistron
Copyright policy )An miRNA-mediated therapy for SCA6 blocks IRES-driven translation of the CACNA1A second cistron
Selective translational blockade of the CACNA1A second cistron using miRNAs may have potential for treating spinocerebellar ataxia type 6.
- Jichi Medical University Japan
- University of Tokyo Japan
- University of Chicago United States
Blotting, Western, Fluorescent Antibody Technique, Internal Ribosome Entry Sites, Real-Time Polymerase Chain Reaction, Immunohistochemistry, Mice, Inbred C57BL, Mice, MicroRNAs, Purkinje Cells, Calcium Channels, N-Type, HEK293 Cells, Genes, Animals, Humans, Immunoprecipitation, Spinocerebellar Ataxias, Calcium Channels, RNA, Small Interfering
Blotting, Western, Fluorescent Antibody Technique, Internal Ribosome Entry Sites, Real-Time Polymerase Chain Reaction, Immunohistochemistry, Mice, Inbred C57BL, Mice, MicroRNAs, Purkinje Cells, Calcium Channels, N-Type, HEK293 Cells, Genes, Animals, Humans, Immunoprecipitation, Spinocerebellar Ataxias, Calcium Channels, RNA, Small Interfering
citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).61 popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.Top 10% influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).Top 10% impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.Top 10%
Citations provided by BIP!Popularity provided by BIP!