New insights into the spatiotemporal localization of prothrombinase in vivo
Copyright policy ) Lacramioara, Ivanciu; Sriram, Krishnaswamy; Rodney M, Camire;
New insights into the spatiotemporal localization of prothrombinase in vivo
Key Points Prothrombinase bound in the vicinity of vascular damage is distributed away from platelets and is largely found on activated endothelium. The activated endothelium plays an unexpectedly important role in supporting prothrombinase assembly and function at the site of damage.
- University of Pennsylvania United States
- Children's Hospital of Philadelphia United States
Blood Platelets, Mice, Inbred BALB C, Thrombin, Thromboplastin, Arterioles, Mice, Platelet Adhesiveness, Factor Va, Factor Xa, Animals, Endothelium, Vascular
Blood Platelets, Mice, Inbred BALB C, Thrombin, Thromboplastin, Arterioles, Mice, Platelet Adhesiveness, Factor Va, Factor Xa, Animals, Endothelium, Vascular
citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).91 popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.Top 10% influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).Top 10% impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.Top 1%
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Citations provided by BIP!
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
Citations provided by BIP!popularityPopularity provided by BIP!
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
Popularity provided by BIP! 91
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