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Applied and Environmental Microbiology
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Applied and Environmental Microbiology
Article . 2013 . Peer-reviewed
License: ASM Journals Non-Commercial TDM
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Applied and Environmental Microbiology
Article . 2013
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https://dx.doi.org/10.1128/aem...
Article
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Identification of Gold Nanoparticle-Resistant Mutants of Saccharomyces cerevisiae Suggests a Role for Respiratory Metabolism in Mediating Toxicity

descriptionPublicationkeyboard_double_arrow_right Article 15 Jan 2013 English Publisher:American Society for MicrobiologyJournal:Applied and Environmental Microbiology, volume 79, pages 728-733 (issn: 0099-2240, eissn: 1098-5336, Copyright policy )
Authors: Mark R, Smith; Matthew G, Boenzli; Vihangi, Hindagolla; Jun, Ding; John M, Miller; James E, Hutchison; Jeffrey A, Greenwood; +2 Authors

doi: 10.1128/aem.01737-12

pmid: 23144132

pmc: PMC3553748

Identification of Gold Nanoparticle-Resistant Mutants of Saccharomyces cerevisiae Suggests a Role for Respiratory Metabolism in Mediating Toxicity

Abstract

ABSTRACT Positively charged gold nanoparticles (0.8-nm core diameter) reduced yeast survival, but not growth, at a concentration of 10 to 100 μg/ml. Among 17 resistant deletion mutants isolated in a genome-wide screen, highly significant enrichment was observed for respiration-deficient mutants lacking genes encoding proteins associated with the mitochondrion.

Related Organizations
Keywords

Microbial Viability, Drug Resistance, Fungal, Nanoparticles, Gold, Saccharomyces cerevisiae, Gene Deletion, Metabolic Networks and Pathways

  • BIP!
    Impact byBIP!
    citations
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 21
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    		 Average
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 Average
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    		 Top 10%
Powered by OpenAIRE graph
citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
21
Average
Average
Top 10%
bronze