Evolution of complexity in miRNA-mediated gene regulation systems
Copyright policy )Evolution of complexity in miRNA-mediated gene regulation systems
Using Arabidopsis microRNA (miRNA)-mediated gene regulation system as a model, we investigated how complex systems evolve with special attention to selection to maintain the systems. We found that the copy number of miRNA genes within each system is a key factor to determine the complexity of the system, indicating a crucial role of gene duplication to increase the complexity. Furthermore, we show that the mode of selection to maintain the systems depend on their complexity levels.
- The Graduate University for Advanced Studies, SOKENDAI Japan
- The University of Texas Health Science Center at Houston United States
- Tohoku University Japan
- Center for Human Genetics United States
Evolution, Molecular, MicroRNAs, Base Sequence, Models, Genetic, Gene Expression Regulation, Plant, RNA, Plant, Multigene Family, Arabidopsis, Selection, Genetic, Genes, Plant
Evolution, Molecular, MicroRNAs, Base Sequence, Models, Genetic, Gene Expression Regulation, Plant, RNA, Plant, Multigene Family, Arabidopsis, Selection, Genetic, Genes, Plant
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