Mitotic Substrates of the Kinase Aurora with Roles in Chromatin Regulation Identified Through Quantitative Phosphoproteomics of Fission Yeast

descriptionPublicationkeyboard_double_arrow_right Article 28 Jun 2011 English Publisher:American Association for the Advancement of Science (AAAS)Journal:Science Signaling, volume 4 (issn: 1945-0877, eissn: 1937-9145,

Authors: André, Koch; Karsten, Krug; Stuart, Pengelley; Boris, Macek; Silke, Hauf;

doi: 10.1126/scisignal.2001588

pmid: 21712547

Mitotic Substrates of the Kinase Aurora with Roles in Chromatin Regulation Identified Through Quantitative Phosphoproteomics of Fission Yeast

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Abstract

System-wide analysis of proteins phosphorylated by the mitotic kinase Aurora in fission yeast suggests widespread functions for this kinase in regulating chromatin dynamics.

Related Organizations

University of Tübingen
Germany
Max Planck Society
Germany

Keywords

Proteomics, Proteome, Aurora Kinases, Schizosaccharomyces, Mitosis, Schizosaccharomyces pombe Proteins, Spindle Apparatus, Phosphorylation, Protein Serine-Threonine Kinases, Chromatin

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