Assignment of the gene locus for the sixth component (C6) of complement in mice to chromosome 15
Copyright policy )Assignment of the gene locus for the sixth component (C6) of complement in mice to chromosome 15
A structural locus (C-6) for the sixth component of complement in mice is assigned to chromosome 15. Three-point linkage analysis indicated that the order of loci is C-6, Gpt-1, Gdc-1, and that the map distances are 25.9 +/- 4.9 between C-6 and Gpt-1, and 36.4 +/- 5.5 between C-6 and Gdc-1. Since Gdc-1 is more distal than Gpt-1, and C-6 is 26 cM away from Gpt-1, it is estimated that the C-6 is proximal to the centromere. In addition, a new C6 form found in AKR mice is described. We propose the designation C6B for it and C-6b for the allele encoding C6B.
Electrophoresis, Mice, Genetic Linkage, Animals, Chromosome Mapping, Alanine Transaminase, Glycerolphosphate Dehydrogenase, Alleles, Complement C6
Electrophoresis, Mice, Genetic Linkage, Animals, Chromosome Mapping, Alanine Transaminase, Glycerolphosphate Dehydrogenase, Alleles, Complement C6
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