Long-Term Outcomes of Congenital Adrenal Hyperplasia
Long-Term Outcomes of Congenital Adrenal Hyperplasia
A plethora of negative long-term outcomes have been associated with congenital adrenal hyperplasia (CAH). The causes are multiple and involve supra-physiological gluco- and mineralocorticoid replacement, excess adrenal androgens both intrauterine and postnatal, elevated steroid precursor and adrenocorticotropic hormone levels, living with a congenital condition as well as the proximity of the cytochrome P450 family 21 subfamily A member 2 (<i>CYP21A2</i>) gene to other genes. This review aims to discuss the different long-term outcomes of CAH.
- Karolinska Institute Sweden
- Karolinska University Hospital Sweden
fertility, Adrenal Hyperplasia, Congenital, neoplasms, Review Article, RC648-665, mortality, Diseases of the endocrine glands. Clinical endocrinology, cardiovascular diseases, mental disorders, bone fracture, Humans, Steroid 21-Hydroxylase
fertility, Adrenal Hyperplasia, Congenital, neoplasms, Review Article, RC648-665, mortality, Diseases of the endocrine glands. Clinical endocrinology, cardiovascular diseases, mental disorders, bone fracture, Humans, Steroid 21-Hydroxylase
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