Radiation inhibits salivary gland function by promoting STIM1 cleavage by caspase-3 and loss of SOCE through a TRPM2-dependent pathway
Copyright policy ) Xibao Liu; Baijuan Gong; Lorena Brito de Souza; Hwei Ling Ong; Krishna P. Subedi; Kwong Tai Cheng; William Swaim; +3 Authors
Xibao Liu; Baijuan Gong; Lorena Brito de Souza; Hwei Ling Ong; Krishna P. Subedi; Kwong Tai Cheng; William Swaim; Changyu Zheng; Yasuo Mori; Indu S. Ambudkar;
Radiation inhibits salivary gland function by promoting STIM1 cleavage by caspase-3 and loss of SOCE through a TRPM2-dependent pathway
Radiation for head and neck cancers causes dry mouth by suppressing store-operated Ca 2+ entry in salivary glands.
- National Institute of Health Pakistan
- Medical Research Council United Kingdom
- National Institute of Dental and Craniofacial Research United States
- MRC Laboratory of Molecular Biology United Kingdom
- National Institutes of Health United States
Membrane Potential, Mitochondrial, Mice, Knockout, ORAI1 Protein, Radiotherapy, Caspase 3, X-Rays, TRPM Cation Channels, Acinar Cells, Salivary Glands, Mitochondria, Mice, Inbred C57BL, Mice, Animals, Humans, Calcium, Calcium Channels, Stromal Interaction Molecule 1, Cells, Cultured
Membrane Potential, Mitochondrial, Mice, Knockout, ORAI1 Protein, Radiotherapy, Caspase 3, X-Rays, TRPM Cation Channels, Acinar Cells, Salivary Glands, Mitochondria, Mice, Inbred C57BL, Mice, Animals, Humans, Calcium, Calcium Channels, Stromal Interaction Molecule 1, Cells, Cultured
citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).44 popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.Top 10% influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).Top 10% impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.Top 10%
citations
Citations provided by BIP!
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
Citations provided by BIP!popularityPopularity provided by BIP!
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
Popularity provided by BIP! 44
Top 10%
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