The murine Mov-34 gene: Full-length cDNA and genomic organization
Copyright policy )The murine Mov-34 gene: Full-length cDNA and genomic organization
The Mov-34 mutation is a recessive embryonic lethal mutation caused by experimental introduction of a recombinant Moloney murine leukemia provirus into the mouse germline. We have cloned a full-length cDNA from the Mov-34 gene, the transcription unit disrupted by the proviral integration. This cDNA is predicted to encode a novel 321-amino acid, 36-kDa protein of unknown function. Overlapping phage lambda clones containing the entire Mov-34 gene have been isolated. The Mov-34 gene spans just over 8 kb and contains seven exons. The 5' flanking region of the Mov-34 gene contains neither "TATA" nor "CAAT" box sequences, and 5' end mapping by primer extension and ribonuclease protection reveal multiple transcription initiation sites.
- Roche (United States) United States
- Whitehead Institute for Biomedical Research United States
- Massachusetts Institute of Technology United States
- Roche (Switzerland) Switzerland
- Roche Institute of Molecular Biology United States
Leukemia, Experimental, Base Sequence, Molecular Sequence Data, DNA, Recombinant, Intracellular Signaling Peptides and Proteins, Proteins, RNA-Binding Proteins, Genes, Recessive, DNA, Exons, Bacteriophage lambda, Recombinant Proteins, Mice, Proviruses, Mutation, Animals, Genes, Lethal, Amino Acid Sequence, Cloning, Molecular, Moloney murine leukemia virus
Leukemia, Experimental, Base Sequence, Molecular Sequence Data, DNA, Recombinant, Intracellular Signaling Peptides and Proteins, Proteins, RNA-Binding Proteins, Genes, Recessive, DNA, Exons, Bacteriophage lambda, Recombinant Proteins, Mice, Proviruses, Mutation, Animals, Genes, Lethal, Amino Acid Sequence, Cloning, Molecular, Moloney murine leukemia virus
citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).24 popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.Average influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).Top 10% impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.Average
Citations provided by BIP!Popularity provided by BIP!