<script type="text/javascript">
<!--
document.write('<div id="oa_widget"></div>');
document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=undefined&type=result"></script>');
-->
</script>

COPY SCRIPT

For further information contact us at helpdesk@openaire.eu

Division of labor in Polycomb group repression

descriptionPublicationkeyboard_double_arrow_right Article 01 Sep 2004 English Publisher:Elsevier BVJournal:Trends in Biochemical Sciences, volume 29, pages 478-485 (issn: 0968-0004,

Authors: Robert E. Kingston; Stuart S. Levine; Ian F. G. King;

doi: 10.1016/j.tibs.2004.07.007

pmid: 15337121

Division of labor in Polycomb group repression

- Summary
- Subjects
- Related research
  (73)
- Metrics

tips_and_updates
Recommended

Abstract

The epigenetic maintenance of gene expression patterns is essential for developing and maintaining the diverse types of cell that cooperate to form the larger organism. Recent data suggest that proteins of the Polycomb group (PcG) use a combination of posttranslational modifications and structural changes to the underlying chromatin structure to maintain silenced epigenetic states. We are now beginning to understand the mechanisms by which the PcG proteins are able to silence genes and to maintain this silencing over many cell divisions.

Related Organizations

Harvard University
United States
Massachusetts General Hospital
United States

Keywords

Models, Molecular, Polycomb Repressive Complex 1, Models, Genetic, Protein Conformation, Polycomb-Group Proteins, Xenopus Proteins, Repressor Proteins, Xenopus laevis, Drosophila melanogaster, Animals, Drosophila Proteins, Gene Silencing, Transcription Factors

73 Research products, page 1 of 8

Pipsqueak, isoform G
2017IsRelatedTo
Trithorax-like, isoform J
2017IsRelatedTo
Chromodomain-helicase-DNA-binding protein Mi-2 homolog
2017IsRelatedTo
Enhancer of polycomb-like protein
2017IsRelatedTo
Polyhomeotic-proximal chromatin protein
2017IsRelatedTo
Enhancer of zeste, isoform C
2017IsRelatedTo
GAGA transcription factor factor, 596 isoform
2017IsRelatedTo
GH14582p
2017IsRelatedTo
EG:BACN25G24.3 protein (Fbgn0004860;ph-d protein)
2017IsRelatedTo
LD31045p
2017IsRelatedTo

chevron_left
1
2
3
4
5
chevron_right

Impact byBIP!

	citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	204
	popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.	Top 10%
	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Top 1%
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Top 1%