Screening large numbers of expression patterns of transcription factors in late stages of the mouse thymus
Copyright policy )Screening large numbers of expression patterns of transcription factors in late stages of the mouse thymus
Transcription factor families are well known to be involved in the intrinsic pathways that regulate the organogenesis, early development, and microenvironment of the thymus. However, identification of the transcription factors (TFs) involved in the late development of the thymus, particularly later than embryonic day 15.5 (E15.5), is progressing slowly. In this study, we used in situ hybridization to screen numerous expression patterns of the TFs involved in the development of the mouse thymus. More than 400 members, including unique TFs and some transcription co-factors, were tested. Among the screened TFs, 160 were found to be expressed in the thymus after E15.5, and 74 of these were expressed in restricted areas.
- Fu Jen Catholic University Taiwan
- Department of Health Taiwan
- Tao Yuan General Hospital Taiwan
- Ministry of Health and Welfare Taiwan
Mice, Inbred C57BL, Mice, Proto-Oncogene Proteins c-ets, Organogenesis, Animals, Gene Expression Regulation, Developmental, Receptors, Cytoplasmic and Nuclear, Thymus Gland, In Situ Hybridization, Transcription Factors
Mice, Inbred C57BL, Mice, Proto-Oncogene Proteins c-ets, Organogenesis, Animals, Gene Expression Regulation, Developmental, Receptors, Cytoplasmic and Nuclear, Thymus Gland, In Situ Hybridization, Transcription Factors
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