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Costal-2: A Scaffold for Kinases Mediates Hedgehog Signaling

descriptionPublicationkeyboard_double_arrow_right Article 01 Feb 2005 English Publisher:Elsevier BVJournal:Developmental Cell, volume 8, pages 140-141 (issn: 1534-5807, Copyright policy )
Authors: Ishii, Shunsuke;

doi: 10.1016/j.devcel.2005.01.004

pmid: 15691757

Costal-2: A Scaffold for Kinases Mediates Hedgehog Signaling

Abstract

Drosophila genetics has identified several components of the Hedgehog signaling pathway, but the mechanism by which they act remains elusive. In this issue of Developmental Cell, a report by Zhang et al. provides evidence that the kinesin-related protein Costal-2 forms a multi-component scaffold that mediates Hedgehog signaling.

Keywords

Animals, Drosophila Proteins, Kinesins, Drosophila, Hedgehog Proteins, Protein Kinases, Developmental Biology, Signal Transduction

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    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    		 Average
    influence
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    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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Powered by OpenAIRE graph
citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
10
Average
Average
Average
hybrid