MOESM3 of Synergistic toxicity in an in vivo model of neurodegeneration through the co-expression of human TDP-43M337V and tauT175D protein

descriptionPublicationkeyboard_double_arrow_right Other literature type 01 Jan 2019Publisher:figshare

Authors: Moszczynski, Alexander; Harvey, Madeline; Niveen Fulcher; Cleusa Oliveira; McCunn, Patrick; Donison, Neil; Bartha, Robert; +3 Authors

doi: 10.6084/m9.figshare.10278314.v1 , 10.6084/m9.figshare.10278314

MOESM3 of Synergistic toxicity in an in vivo model of neurodegeneration through the co-expression of human TDP-43M337V and tauT175D protein

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Abstract

Additional file 3: Figure S3. CatWalk hind paw stride length and body speed were disrupted in ChAT-tTA/TRE-TDP-43M337V rats upon doxycycline (DOX) reduction over time. A) The interaction between the TDP-43M337V and DOX reduction time on hind paw swing; the duration of time the paw was not in contact with the glass plate was not significant (n ≥ 6/group, p = 0.178). B) There was no statistically significant interaction between the TDP-43M337V and DOX reduction time on hind paw swing speed (speed of the paw while taking a step), however we were approaching significance (n ≥ 6/group, p = 0.059).

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