Cloning, tissue-specific expression, gene structure and chromosomal localization of human phosphatidylcholine transfer protein
Copyright policy )Cloning, tissue-specific expression, gene structure and chromosomal localization of human phosphatidylcholine transfer protein
Phosphatidylcholine transfer protein (PC-TP) is a cytosolic protein that catalyzes intermembrane transfer of phosphatidylcholines in vitro. We have cloned a cDNA encoding the human ortholog of PC-TP and have determined its tissue-specific expression as well as genomic organization. Radiation hybrid mapping localized the human gene, PCTP, to chromosome 17q21-22 and PCR-based single strand conformation polymorphism analysis of an interspecific backcross assigned mouse Pctp to the region of syntenic conservation on chromosome 11.
- University of Illinois at Chicago United States
- Albert Einstein College of Medicine United States
- Brigham and Women's Faulkner Hospital United States
- Harvard University United States
DNA, Complementary, Base Sequence, Molecular Sequence Data, Chromosome Mapping, Gene Expression, Phosphatidylethanolamine Binding Protein, Androgen-Binding Protein, Organ Specificity, Humans, Amino Acid Sequence, Cloning, Molecular, Phospholipid Transfer Proteins, Carrier Proteins, Chromosomes, Human, Pair 17
DNA, Complementary, Base Sequence, Molecular Sequence Data, Chromosome Mapping, Gene Expression, Phosphatidylethanolamine Binding Protein, Androgen-Binding Protein, Organ Specificity, Humans, Amino Acid Sequence, Cloning, Molecular, Phospholipid Transfer Proteins, Carrier Proteins, Chromosomes, Human, Pair 17
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