Identification of Protein Tyrosine Phosphatases Expressed in Murine Male Germ Cells
Copyright policy )Identification of Protein Tyrosine Phosphatases Expressed in Murine Male Germ Cells
We cloned five cDNAs encoding putative protein tyrosine phosphatases (PTPs; protein-tyrosine-phosphatase phosphohydrolase, EC 3.1.3.48) from the murine testis by using degenerate primers and the polymerase chain reaction cloning technique. Two of them were identical to the mouse cytoplasmic PTP and PTP-1B. The remaining three were likely to represent the murine counterparts of human PTP delta, human PTP epsilon, and rat striatum-enriched PTP. The cells expressing these genes were determined either by in situ hybridization histochemistry or by Northern blot hybridization. Moreover, Northern blot hybridization revealed that the transcripts of PTP-1B, mouse cytoplasmic PTP and the murine homologue of human PTP delta were quantitatively and/or structurally regulated during germ cell development, suggesting their roles in spermatogenesis.
- Kyoto University Japan
Male, DNA, Complementary, Sequence Homology, Amino Acid, Polymerase Chain Reaction, Spermatids, Corpus Striatum, Mice, Mutant Strains, Rats, Isoenzymes, Mice, Spermatocytes, Animals, Humans, Amino Acid Sequence, Sexual Maturation, Cloning, Molecular, Protein Tyrosine Phosphatases, Conserved Sequence, In Situ Hybridization, DNA Primers
Male, DNA, Complementary, Sequence Homology, Amino Acid, Polymerase Chain Reaction, Spermatids, Corpus Striatum, Mice, Mutant Strains, Rats, Isoenzymes, Mice, Spermatocytes, Animals, Humans, Amino Acid Sequence, Sexual Maturation, Cloning, Molecular, Protein Tyrosine Phosphatases, Conserved Sequence, In Situ Hybridization, DNA Primers
citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).28 popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.Average influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).Top 10% impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.Top 10%
Citations provided by BIP!Popularity provided by BIP!