Tag Team Ubiquitin Ligases
Copyright policy ) Kleiger, Gary; Deshaies, Raymond;
Tag Team Ubiquitin Ligases
Cullin-RING (CRL) and RING1-IBR-RING2 (RBR) are two distinct types of ubiquitin ligases. In this issue, Scott et al. show that CRLs activate the RBR enzyme ARIH1 to initiate ubiquitin chains on CRL substrates, thereby marking an unexpected and important advance in our understanding of both enzymes.
- University of Nevada, Las Vegas United States
- California Institute of Technology United States
- Nevada System of Higher Education United States
- Howard Hughes Medical Institute United States
570, Ubiquitin, Ubiquitin-Protein Ligases, 610, Humans, Cullin Proteins
570, Ubiquitin, Ubiquitin-Protein Ligases, 610, Humans, Cullin Proteins
citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).12 popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.Top 10% influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).Average impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.Top 10%
citations
Citations provided by BIP!
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
Citations provided by BIP!popularityPopularity provided by BIP!
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
Popularity provided by BIP! 12
Top 10%
Average
Top 10%
hybrid