Sequence and organization of the human mitochondrial genome
Copyright policy )Sequence and organization of the human mitochondrial genome
The complete sequence of the 16,569-base pair human mitochondrial genome is presented. The genes for the 12S and 16S rRNAs, 22 tRNAs, cytochrome c oxidase subunits I, II and III, ATPase subunit 6, cytochrome b and eight other predicted protein coding genes have been located. The sequence shows extreme economy in that the genes have none or only a few noncoding bases between them, and in many cases the termination codons are not coded in the DNA but are created post-transcriptionally by polyadenylation of the mRNAs.
- Medical Research Council United Kingdom
- University System of Ohio United States
- Australian National University Australia
- University of Leicester United Kingdom
- University of California, Los Angeles United States
DNA Replication, Science & Technology, Base Sequence, Transcription, Genetic, Nucleic Acid Precursors, Peptide Chain Termination, Translational, Biological Evolution, DNA, Mitochondrial, Multidisciplinary Sciences, Genes, RNA, Transfer, RNA, Ribosomal, Science & Technology - Other Topics, Humans, Codon, Peptide Chain Initiation, Translational
DNA Replication, Science & Technology, Base Sequence, Transcription, Genetic, Nucleic Acid Precursors, Peptide Chain Termination, Translational, Biological Evolution, DNA, Mitochondrial, Multidisciplinary Sciences, Genes, RNA, Transfer, RNA, Ribosomal, Science & Technology - Other Topics, Humans, Codon, Peptide Chain Initiation, Translational
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