Integrative Biology Approach Identifies Cytokine Targeting Strategies for Psoriasis
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Perera, Gayathri K.; Ainali, Chrysanthi; Semenova, Ekaterina; Hundhausen, Christian; Barinaga, Guillermo; Kassen, Deepika; Williams, Andrew E.; +9 Authors
Perera, Gayathri K.; Ainali, Chrysanthi; Semenova, Ekaterina; Hundhausen, Christian; Barinaga, Guillermo; Kassen, Deepika; Williams, Andrew E.; Mirza, Muddassar M.; Balazs, Mercedesz; Wang, Xiaoting; Rodriguez, Robert Sanchez; Alendar, Andrej; Barker, Jonathan; Tsoka, Sophia; Ouyang, Wenjun; Nestle, Frank O.;
Integrative Biology Approach Identifies Cytokine Targeting Strategies for Psoriasis
The serine/threonine kinase PIM1 is a critical checkpoint for human skin inflammation and potential target in psoriasis.
United Kingdom
- West Middlesex University Hospital United Kingdom
- GENENTECH INC United States
- Kings College London, University of London United Kingdom
- Guy's and St Thomas' NHS Foundation Trust United Kingdom
- Chelsea and Westminster Hospital NHS Foundation Trust United Kingdom
SUSCEPTIBILITY LOCI, 610, Interleukin-22, MECHANISMS, ACTIVATION, Mice, SKIN INFLAMMATION, 616, IL-22, Animals, Humans, Psoriasis, Mice, Knockout, Interleukins, Antibodies, Monoclonal, MOUSE MODEL, ASSOCIATION, NETWORKS, Disease Models, Animal, T-CELLS, INNATE IMMUNITY
SUSCEPTIBILITY LOCI, 610, Interleukin-22, MECHANISMS, ACTIVATION, Mice, SKIN INFLAMMATION, 616, IL-22, Animals, Humans, Psoriasis, Mice, Knockout, Interleukins, Antibodies, Monoclonal, MOUSE MODEL, ASSOCIATION, NETWORKS, Disease Models, Animal, T-CELLS, INNATE IMMUNITY
citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).43 popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.Top 10% influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).Top 10% impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.Top 10%
citations
Citations provided by BIP!
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
Citations provided by BIP!popularityPopularity provided by BIP!
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
Popularity provided by BIP! 43
Top 10%
Top 10%
Top 10%
