A transmembrane protein–tyrosine phosphatase receptor type C (CD45) exon A point mutation (77 C to G) is not associated with the development of type 1 diabetes mellitus in a German population
Copyright policy )A transmembrane protein–tyrosine phosphatase receptor type C (CD45) exon A point mutation (77 C to G) is not associated with the development of type 1 diabetes mellitus in a German population
SummaryTo investigate whether a C to G transversion at position 77 in exon A of the CD45 gene is associated with the development of diabetes mellitus type 1 (T1D), we studied 165 patients and 220 control individuals. The frequency of the 77G allele in the control group was 1.1%, which was not significantly different from the 1.2% found in the patient group (P = 0.922). The C to G transversion does not seem to be associated with susceptibility for T1D.
- Institute for Transfusion Medicine United States
- Jena University Hospital Germany
- Friedrich Schiller University Jena Germany
Protein Tyrosine Phosphatase, Non-Receptor Type 1, Genotype, Exons, Sequence Analysis, DNA, Diabetes Mellitus, Type 1, Germany, Humans, Leukocyte Common Antigens, Point Mutation, Genetic Predisposition to Disease
Protein Tyrosine Phosphatase, Non-Receptor Type 1, Genotype, Exons, Sequence Analysis, DNA, Diabetes Mellitus, Type 1, Germany, Humans, Leukocyte Common Antigens, Point Mutation, Genetic Predisposition to Disease
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