MacA, a Diheme c -Type Cytochrome Involved in Fe(III) Reduction by Geobacter sulfurreducens
MacA, a Diheme c -Type Cytochrome Involved in Fe(III) Reduction by Geobacter sulfurreducens
ABSTRACT A 36-kDa diheme c -type cytochrome abundant in Fe(III)-respiring Geobacter sulfurreducens , designated MacA, was more highly expressed during growth with Fe(III) as the electron acceptor than with fumarate. Although MacA has homology to proteins with in vitro peroxidase activity, deletion of macA had no impact on response to oxidative stress. However, the capacity for Fe(III) reduction was greatly diminished, indicating that MacA, which is predicted to be localized in the periplasm, is a key intermediate in electron transfer to Fe(III).
- UNIVERSITY OF MASSACHUSETTS United States
- University of Massachusetts System United States
- Universidad Nacional Autónoma de México
- Universidad Nacional Autónoma de México
- Department of Microbiology United States
Deltaproteobacteria, Electron Transport, Bacterial Proteins, Molecular Sequence Data, Cytochrome c Group, Amino Acid Sequence, Microbiology, Ferric Compounds, Oxidation-Reduction, Gene Deletion
Deltaproteobacteria, Electron Transport, Bacterial Proteins, Molecular Sequence Data, Cytochrome c Group, Amino Acid Sequence, Microbiology, Ferric Compounds, Oxidation-Reduction, Gene Deletion
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