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DIGITAL.CSIC
Article . 2016 . Peer-reviewed
Data sources: DIGITAL.CSIC
Seminars in Cell and Developmental Biology
Article . 2014 . Peer-reviewed
Data sources: Crossref
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Genetics and mechanisms of ovarian cancer: Parallels between Drosophila and humans

Authors: Rosales-Nieves, Alicia E.; González-Reyes, Acaimo;

Genetics and mechanisms of ovarian cancer: Parallels between Drosophila and humans

Abstract

Considering the degree of detail available at the genetic and cellular levels, the Drosophila ovary stands out as a powerful system to identify new players in the regulation of key aspects of cancer progression. In this review, we will comment on how the use of the Drosophila ovary has helped to elucidate some of the molecular bases of ovarian malignancies and to identify and characterize critical tumour suppressor genes and oncogenes with an impact in human pathologies.

Keywords

Ovarian Neoplasms, Hippo pathway, Ovary, Oncogenes, Epithelium, Ovarian surface epithelium, Border cell migration, Cell Movement, Animals, Humans, Drosophila, Female, Ovarian carcinoma, Follicular epithelium, Signal Transduction

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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
views
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17
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28
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