Downloads provided by UsageCountsGenetics and mechanisms of ovarian cancer: Parallels between Drosophila and humans
Genetics and mechanisms of ovarian cancer: Parallels between Drosophila and humans
Considering the degree of detail available at the genetic and cellular levels, the Drosophila ovary stands out as a powerful system to identify new players in the regulation of key aspects of cancer progression. In this review, we will comment on how the use of the Drosophila ovary has helped to elucidate some of the molecular bases of ovarian malignancies and to identify and characterize critical tumour suppressor genes and oncogenes with an impact in human pathologies.
Ovarian Neoplasms, Hippo pathway, Ovary, Oncogenes, Epithelium, Ovarian surface epithelium, Border cell migration, Cell Movement, Animals, Humans, Drosophila, Female, Ovarian carcinoma, Follicular epithelium, Signal Transduction
Ovarian Neoplasms, Hippo pathway, Ovary, Oncogenes, Epithelium, Ovarian surface epithelium, Border cell migration, Cell Movement, Animals, Humans, Drosophila, Female, Ovarian carcinoma, Follicular epithelium, Signal Transduction
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