Alpha-2-HS-Glycoprotein Polymorphism Detected in Human Urine by Isoelectric Focusing and Immunoblotting

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 1988 English Publisher:S. Karger AGJournal:Human Heredity, volume 38, pages 207-210 (issn: 0001-5652, eissn: 1423-0062,

Authors: K, Kishi; T, Yasuda; Y, Ikehara;

doi: 10.1159/000153786

pmid: 3169794

Alpha-2-HS-Glycoprotein Polymorphism Detected in Human Urine by Isoelectric Focusing and Immunoblotting

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Abstract

Polymorphism of alpha 2-HS-glycoprotein (AHSG) was revealed in human urine by isoelectric focusing and immunoblotting on polyacrylamide gels. More than 200 urine samples were examined in this manner and correct AHSG typing of the urine samples was achieved, in comparison with the results of direct grouping for plasma. Three phenotypes, AHSG 1, 2-1 and 2, were observed and found to be determined by two common alleles, AHSG*1 and AHSG*2. The frequencies of AHSG*1 and AHSG*2 calculated in a Japanese population were 0.7637 and 0.2363, respectively.

Related Organizations

American Board of Legal Medicine
United States

Keywords

Phenotype, Polymorphism, Genetic, Japan, alpha-2-HS-Glycoprotein, Immunoblotting, Humans, Blood Proteins, Isoelectric Focusing, Alleles

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