Antitumor Agents II: Eupatolide, a New Cytotoxic Principle from Eupatorium formosanum HAY

descriptionPublicationkeyboard_double_arrow_right Article 01 Apr 1972 English Publisher:Elsevier BVJournal:Journal of Pharmaceutical Sciences, volume 61, pages 629-631 (issn: 0022-3549,

Authors: K H, Lee; H C, Huang; E S, Huang; H, Furukawa;

doi: 10.1002/jps.2600610432

pmid: 4335375

Antitumor Agents II: Eupatolide, a New Cytotoxic Principle from Eupatorium formosanum HAY

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Abstract

An alcoholic extract of the aboveground parts of Eupatorium formosanum, which showed significant inhibitory activity of the in vitro growth of tissue culture cells derived from human epidermoid carcinoma of larynx (H.Ep.-2), was examined and provided a new cytotoxic principle, eupatolide, a germacranolide sesquiterpene lactone.

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University of North Carolina at Chapel Hill
United States

Keywords

Magnetic Resonance Spectroscopy, Infrared Rays, Plant Extracts, Terpenes, Spectrum Analysis, Carcinoma, Antineoplastic Agents, Haplorhini, Simian virus 40, Mass Spectrometry, Cell Line, Lactones, Structure-Activity Relationship, Cell Transformation, Neoplastic, Animals, Humans, Laryngeal Neoplasms, Lung, Sesquiterpenes

9 Research products, page 1 of 1

Eupatolide inhibits lipopolysaccharide-induced COX-2 and iNOS expression in RAW264.7 cells by inducing proteasomal degradation of TRAF6
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Corrigendum to “Eupatolide inhibits lipopolysaccharide-induced COX-2 and iNOS expression in RAW264.7 cells by inducing proteasomal degradation of TRAF6” [Eur. J. Pharmacol. 636 (2010) 173–180]
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