Efficient development of stable and highly functionalised peptides targeting the CK2α/CK2β protein–protein interaction
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Eleanor L Atkinson; David R. Spring; David Baker; Hannah F. Sore; Marko Hyvönen; Daniel H. O' Donovan; Paul Brear; +5 Authors
Eleanor L Atkinson; David R. Spring; David Baker; Hannah F. Sore; Marko Hyvönen; Daniel H. O' Donovan; Paul Brear; Yaw Sing Tan; Chandra S. Verma; Chandra S. Verma; Chandra S. Verma; J. Iegre;
Efficient development of stable and highly functionalised peptides targeting the CK2α/CK2β protein–protein interaction
This work describes the efficient development of functionalised, cell-permeable, and stable peptide inhibitors of the protein–protein interaction of CK2.
- Bioinformatics Institute Russian Federation
- University of Cambridge United Kingdom
- Nanyang Technological University Singapore
- Department of Chemistry Switzerland
- ASTRAZENECA UK LIMITED United Kingdom
Biomedical, :Biological sciences [Science], 540, 0601 Biochemistry and Cell Biology, 0305 Organic Chemistry, 620, Chemistry, Basic Science, 5.1 Pharmaceuticals, Protein–Protein Interaction, Peptides
Biomedical, :Biological sciences [Science], 540, 0601 Biochemistry and Cell Biology, 0305 Organic Chemistry, 620, Chemistry, Basic Science, 5.1 Pharmaceuticals, Protein–Protein Interaction, Peptides
citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).27 popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.Top 10% influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).Average impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.Top 10%
citations
Citations provided by BIP!
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
Citations provided by BIP!popularityPopularity provided by BIP!
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
Popularity provided by BIP! 27
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