Issues and updates: evaluating estrogen receptor-α, progesterone receptor, and HER2 in breast cancer
pmid: 20436503
Issues and updates: evaluating estrogen receptor-α, progesterone receptor, and HER2 in breast cancer
There are currently three prognostic/predictive biomarkers used in routine clinical management of patients with breast cancer, and their assessment is mandatory. They include estrogen receptor-alpha (ERalpha), progesterone receptor (PgR), and the HER2 oncogene/oncoprotein. This paper briefly reviews the assessment of ERalpha, PgR, and HER2 in breast cancer, emphasizing recent progress and persistent controversies.
- University of Mary United States
- Washington University in St. Louis United States
Receptor, ErbB-2, Biomarkers, Tumor, Estrogen Receptor alpha, Humans, Breast Neoplasms, Female, Genetic Predisposition to Disease, Genes, erbB-2, Receptors, Progesterone, Immunohistochemistry
Receptor, ErbB-2, Biomarkers, Tumor, Estrogen Receptor alpha, Humans, Breast Neoplasms, Female, Genetic Predisposition to Disease, Genes, erbB-2, Receptors, Progesterone, Immunohistochemistry
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