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Modern Pathology
Article
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Modern Pathology
Article . 2010 . Peer-reviewed
License: Elsevier Non-Commercial
Data sources: Crossref
Modern Pathology
Article . 2010
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Issues and updates: evaluating estrogen receptor-α, progesterone receptor, and HER2 in breast cancer

Authors: D Craig, Allred;

Issues and updates: evaluating estrogen receptor-α, progesterone receptor, and HER2 in breast cancer

Abstract

There are currently three prognostic/predictive biomarkers used in routine clinical management of patients with breast cancer, and their assessment is mandatory. They include estrogen receptor-alpha (ERalpha), progesterone receptor (PgR), and the HER2 oncogene/oncoprotein. This paper briefly reviews the assessment of ERalpha, PgR, and HER2 in breast cancer, emphasizing recent progress and persistent controversies.

Related Organizations
Keywords

Receptor, ErbB-2, Biomarkers, Tumor, Estrogen Receptor alpha, Humans, Breast Neoplasms, Female, Genetic Predisposition to Disease, Genes, erbB-2, Receptors, Progesterone, Immunohistochemistry

  • BIP!
    Impact byBIP!
    citations
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    170
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Top 1%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Top 10%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Top 10%
Powered by OpenAIRE graph
citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
170
Top 1%
Top 10%
Top 10%
bronze
Related to Research communities
Cancer Research