Functional Anatomy of the Trimer Apex Reveals Key Hydrophobic Constraints That Maintain the HIV-1 Envelope Spike in a Closed State
Copyright policy )Functional Anatomy of the Trimer Apex Reveals Key Hydrophobic Constraints That Maintain the HIV-1 Envelope Spike in a Closed State
Elucidating the structure and function of the HIV-1 outer envelope proteins is critical for the design of an effective vaccine. Despite the availability of many high-resolution structures, key functional correlates in the envelope trimer remain undefined.
- National Institute of Health Pakistan
- Johns Hopkins Medicine United States
- National Institute of Allergy and Infectious Diseases United States
- Johns Hopkins University School of Medicine United States
- John Hopkins University School of Medecine United States
Amino Acid Motifs, env Gene Products, Human Immunodeficiency Virus, HIV Infections, HIV Antibodies, Microbiology, Antibodies, Neutralizing, QR1-502, Mutation, HIV-1, Humans, Amino Acid Sequence, Hydrophobic and Hydrophilic Interactions, Research Article
Amino Acid Motifs, env Gene Products, Human Immunodeficiency Virus, HIV Infections, HIV Antibodies, Microbiology, Antibodies, Neutralizing, QR1-502, Mutation, HIV-1, Humans, Amino Acid Sequence, Hydrophobic and Hydrophilic Interactions, Research Article
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