Essential role of BRG, the ATPase subunit of BAF chromatin remodeling complexes, in leukemia maintenance
Copyright policy )Essential role of BRG, the ATPase subunit of BAF chromatin remodeling complexes, in leukemia maintenance
Key Points Quantitative proteomics identifies BRG as the main ATPase of BAF complexes expressed in leukemia. BRG is essential for the proliferation of leukemic cells.
- Institute for Research in Immunology and Cancer Canada
- Stanford University United States
- Howard Hughes Medical Institute United States
- University of Montreal Canada
Mice, Knockout, Reverse Transcriptase Polymerase Chain Reaction, DNA Helicases, Nuclear Proteins, Chromatin Assembly and Disassembly, Flow Cytometry, Hematopoietic Stem Cells, Real-Time Polymerase Chain Reaction, Mice, Inbred C57BL, Blotting, Southern, Disease Models, Animal, Leukemia, Myeloid, Acute, Mice, Tandem Mass Spectrometry, Animals, Humans, RNA, Messenger, Chromatography, Liquid, Transcription Factors
Mice, Knockout, Reverse Transcriptase Polymerase Chain Reaction, DNA Helicases, Nuclear Proteins, Chromatin Assembly and Disassembly, Flow Cytometry, Hematopoietic Stem Cells, Real-Time Polymerase Chain Reaction, Mice, Inbred C57BL, Blotting, Southern, Disease Models, Animal, Leukemia, Myeloid, Acute, Mice, Tandem Mass Spectrometry, Animals, Humans, RNA, Messenger, Chromatography, Liquid, Transcription Factors
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