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Science Translational Medicine
Article
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Science Translational Medicine
Article . 2014 . Peer-reviewed
Data sources: Crossref
Science Translational Medicine
Article . 2015
Data sources: Europe PubMed Central
https://dx.doi.org/10.1126/sci...
Article
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Aldehyde dehydrogenase-2 regulates nociception in rodent models of acute inflammatory pain

descriptionPublicationkeyboard_double_arrow_right Article 27 Aug 2014 English Publisher:American Association for the Advancement of Science (AAAS)Journal:Science Translational Medicine, volume 6 (issn: 1946-6234, eissn: 1946-6242, Copyright policy )
Authors: Vanessa O, Zambelli; Eric R, Gross; Che-Hong, Chen; Vanessa P, Gutierrez; Yara, Cury; Daria, Mochly-Rosen;

doi: 10.1126/scitranslmed.3009539

pmid: 25163478

pmc: PMC4234033

Aldehyde dehydrogenase-2 regulates nociception in rodent models of acute inflammatory pain

Abstract

Pain sensitivity can be modulated by an enzyme that degrades aldehydes in rodents, pointing to a promising therapeutic target.

Related Organizations
Keywords

Inflammation, Nociception, Heterozygote, Behavior, Animal, Aldehyde Dehydrogenase, Mitochondrial, Acetaldehyde, Aldehyde Dehydrogenase, Acute Pain, Rats, Enzyme Activation, Mice, Inbred C57BL, Mitochondrial Proteins, Disease Models, Animal, Hyperalgesia, Formaldehyde, Benzamides, Animals, Benzodioxoles

  • BIP!
    Impact byBIP!
    citations
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 95
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    		 Top 1%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 Top 10%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    		 Top 10%
Powered by OpenAIRE graph
citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
95
Top 1%
Top 10%
Top 10%
bronze
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