yes-related protooncogene, syn, belongs to the protein-tyrosine kinase family.
Copyright policy )yes-related protooncogene, syn, belongs to the protein-tyrosine kinase family.
An src/yes-related novel gene named syn (SYN in human gene nomenclature) has been identified in the human genome on chromosome 6 and characterized by molecular cloning. Nucleotide sequence analysis of cDNA clones showed that the c-syn gene could encode a protein-tyrosine kinase that is very similar in primary structure to the v-yes and human c-src proteins. A 2.8-kilobase transcript of the c-syn gene, which differs in size from those of the c-yes, c-src, and c-fgr genes, was observed in various cell types. These results show that syn is a new member of the tyrosine kinase oncogene family.
- University of Tokyo Japan
Chromosomes, Human, 6-12 and X, Base Sequence, Gene Expression Regulation, Proto-Oncogene Proteins, Proto-Oncogenes, Humans, Amino Acid Sequence, DNA, Cloning, Molecular, Protein-Tyrosine Kinases
Chromosomes, Human, 6-12 and X, Base Sequence, Gene Expression Regulation, Proto-Oncogene Proteins, Proto-Oncogenes, Humans, Amino Acid Sequence, DNA, Cloning, Molecular, Protein-Tyrosine Kinases
citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).265 popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.Top 10% influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).Top 1% impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.Top 1%
Citations provided by BIP!Popularity provided by BIP!