KPNA6 is a Cofactor of ANP32A/B in Supporting Influenza Virus Polymerase Activity
KPNA6 is a Cofactor of ANP32A/B in Supporting Influenza Virus Polymerase Activity
Host factor ANP32 plays a fundamental role in supporting the polymerase activity of influenza viruses, but the underlying mechanism is largely unknown. Here, we propose that KPNA6 is involved in the function of ANP32A/B to support influenza virus polymerase by interacting with both vRNP and ANP32A/B.
- Harbin Veterinary Research Institute China (People's Republic of)
- Chinese Academy of Agricultural Sciences China (People's Republic of)
- State Key Laboratory of Veterinary Biotechnology China (People's Republic of)
Cell Nucleus, alpha Karyopherins, KPNA6, Nuclear Proteins, RNA-Binding Proteins, Genome, Viral, Orthomyxoviridae, RNA-Dependent RNA Polymerase, Virus Replication, Microbiology, QR1-502, vRNP, polymerase, Viral Proteins, HEK293 Cells, Influenza A virus, Animals, Humans, ANP32A, ANP32B, influenza, Research Article
Cell Nucleus, alpha Karyopherins, KPNA6, Nuclear Proteins, RNA-Binding Proteins, Genome, Viral, Orthomyxoviridae, RNA-Dependent RNA Polymerase, Virus Replication, Microbiology, QR1-502, vRNP, polymerase, Viral Proteins, HEK293 Cells, Influenza A virus, Animals, Humans, ANP32A, ANP32B, influenza, Research Article
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