Human Leukocyte Antigens B8-DRB1*03 in Pediatric Patients With Nephropathia Epidemica Caused by Puumala Hantavirus
Copyright policy ) Jukka, Mustonen; Niilo-Pekka, Huttunen; Jukka, Partanen; Maija, Baer; Antti, Paakkala; Olli, Vapalahti; Matti, Uhari;
Human Leukocyte Antigens B8-DRB1*03 in Pediatric Patients With Nephropathia Epidemica Caused by Puumala Hantavirus
In adults, HLA haplotype B8-DRB1*03 is clearly associated with a severe clinical course of nephropathia epidemica caused by Puumala hantavirus. We investigated whether the same applies in pediatric patients. This HLA haplotype was found in 20 of 39 (51%) of the patients, a significantly higher figure than in the Finnish population (19%). There were, however, no significant differences in the clinical picture between patients with and without HLA B8-DRB1*03.
- University of Helsinki Finland
- Oulu University Hospital Finland
- Tampere University Hospital Finland
- Tampere University Finland
Male, Adolescent, Child, Preschool, Hemorrhagic Fever with Renal Syndrome, Humans, Female, Child, Puumala virus, HLA-B8 Antigen
Male, Adolescent, Child, Preschool, Hemorrhagic Fever with Renal Syndrome, Humans, Female, Child, Puumala virus, HLA-B8 Antigen
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This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
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