Infrequent occurrence of mutations in the PH domain of LNK in patients with JAK2 mutation-negative 'idiopathic' erythrocytosis
Copyright policy )Infrequent occurrence of mutations in the PH domain of LNK in patients with JAK2 mutation-negative 'idiopathic' erythrocytosis
LNK (SH2B3) belongs to a family of adaptor proteins that contain a proline-rich N-terminal dimerization domain, a pleckstrin homology domain (PH), an Src homology-2 domain (SH2), and a conserved C-terminal tyrosine residue. By binding to cytokine receptors and JAK2 through the SH2 domain, LNK
- New York University Italy
- University of Florence Italy
Male, Intracellular Signaling Peptides and Proteins, Proteins, Polycythemia, Janus Kinase 2, Middle Aged, Cohort Studies, Mutation, erythrocytosis, Humans, Diseases of the blood and blood-forming organs, Female, RC633-647.5, Adaptor Proteins, Signal Transducing, Aged
Male, Intracellular Signaling Peptides and Proteins, Proteins, Polycythemia, Janus Kinase 2, Middle Aged, Cohort Studies, Mutation, erythrocytosis, Humans, Diseases of the blood and blood-forming organs, Female, RC633-647.5, Adaptor Proteins, Signal Transducing, Aged
citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).27 popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.Top 10% influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).Top 10% impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.Top 10%
Citations provided by BIP!Popularity provided by BIP!