Bulletin of Taras Shevchenko National University of Kyiv. Series : Problems of Physiological Functions Regulation
Article . 2017 . Peer-reviewed
Data sources: Crossref
Bulletin of Taras Shevchenko National University of Kyiv. Series : Problems of Physiological Functions Regulation
Article
License: CC BY
Data sources: UnpayWall
Influence of C60FAS on the speed-power parameters of the tetanic contraction of muscle soleus on the conditions of experimentally-induced ischemia at different durations in alcoholised rats
ВПЛИВ ВРС60 НА ШВИДКІСНО-СИЛОВІ ПАРАМЕТРИ ТЕТАНІЧНОГО СКОРОЧЕННЯ MUSCLE SOLEUS АЛКОГОЛІЗОВАНИХ ЩУРІВ ЗА УМОВИ ЕКСПЕРИМЕНТАЛЬНО-ІНДУКОВАНОЇ ІШЕМІЇ РІЗНОЇ ТРИВАЛОСТІ
Authors: S. Zay; O. Motuzyuk; V. Belobrov; D. Vulitska; O. Nozdrenko;
Influence of C60FAS on the speed-power parameters of the tetanic contraction of muscle soleus on the conditions of experimentally-induced ischemia at different durations in alcoholised rats
Abstract
In the article presented the results of tenzometric studies of the effect of C60FAS (concentration 0.15 mg / ml) at a dose of 1 mg / kg ON the speed-power parameters of the tetanic reduction of muscle soleus under conditions of ischemia in chronic alcoholic rats during 1-hour and 2-hour. The synergistic effect of ischemic injury and alcoholic intoxication, as compared to the native muscle, is manifested in reducing the reduction power to 26,25 ± 3,23 and 20,2 ± 2,45 (p≤0,01), and an increase in the time to achieve it the maximum values for 1.33 ± 0.12s and 1.45 ± 0.15s (p≤0.01) respectively. It is shown that if the intraperitoneal administration of the VRC60 solution is given, these indices are likely to increase.
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