CHUK, a Conserved Helix-Loop-Helix Ubiquitous Kinase, Maps to Human Chromosome 10 and Mouse Chromosome 19
Copyright policy )CHUK, a Conserved Helix-Loop-Helix Ubiquitous Kinase, Maps to Human Chromosome 10 and Mouse Chromosome 19
Helix-loop-helix proteins contain stretches of DNA that encode two amphipathic alpha-helices joined by a loop structure and are involved in protein dimerization and transcriptional regulation essential to a variety of cellular processes. CHUK, a newly described conserved helix-loop-helix ubiquitous kinase, was mapped by somatic cell hybrid analyses to human Chr 10q24-q25. Chuk and a related sequence, Chuk-rs1, were mapped to mouse chromosomes 19 and 16, respectively, by a combination of somatic cell hybrid, recombinant inbred, and backcross analyses.
- National Institutes of Health United States
- State University of New York at Potsdam United States
- State University of New York United States
Leucine Zippers, DNA, Complementary, Chromosomes, Human, Pair 10, Helix-Loop-Helix Motifs, Molecular Sequence Data, Chromosome Mapping, Mice, Inbred Strains, Protein Serine-Threonine Kinases, Chromosomes, I-kappa B Kinase, Mice, Cricetinae, Animals, Humans
Leucine Zippers, DNA, Complementary, Chromosomes, Human, Pair 10, Helix-Loop-Helix Motifs, Molecular Sequence Data, Chromosome Mapping, Mice, Inbred Strains, Protein Serine-Threonine Kinases, Chromosomes, I-kappa B Kinase, Mice, Cricetinae, Animals, Humans
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