Arabidopsis Forkhead‐Associated Domain Protein 3 negatively regulates peroxisome division
Copyright policy )Arabidopsis Forkhead‐Associated Domain Protein 3 negatively regulates peroxisome division
SummaryPeroxisomes are ubiquitous and dynamic eukaryotic organelles capable of altering their abundance in response to environmental and developmental cues, yet the regulatory mechanism of plant peroxisome division/proliferation is unclear. To identify transcriptional regulators of the peroxisome division factor gene PEX11b, we performed a nuclear pull‐down experiment and identified Arabidopsis Forkhead‐Associated Domain Protein 3 (FHA3) as a novel protein that binds to the promoter of PEX11b. Our data supported the conclusion that, in contrast to the previously identified HY5 HOMOLOG (HYH) protein that promotes the transcription of PEX11b, FHA3 is a negative regulator of PEX11b expression and peroxisome division.
- Michigan State University United States
DNA-Binding Proteins, Peroxins, Arabidopsis Proteins, Gene Expression Regulation, Plant, Arabidopsis, Peroxisomes, Membrane Proteins, Carrier Proteins
DNA-Binding Proteins, Peroxins, Arabidopsis Proteins, Gene Expression Regulation, Plant, Arabidopsis, Peroxisomes, Membrane Proteins, Carrier Proteins
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