Building ProteomeTools based on a complete synthetic human proteome
Copyright policy )Building ProteomeTools based on a complete synthetic human proteome
We describe ProteomeTools, a project building molecular and digital tools from the human proteome to facilitate biomedical research. Here we report the generation and multimodal liquid chromatography-tandem mass spectrometry analysis of >330,000 synthetic tryptic peptides representing essentially all canonical human gene products, and we exemplify the utility of these data in several applications. The resource (available at http://www.proteometools.org) will be extended to >1 million peptides, and all data will be shared with the community via ProteomicsDB and ProteomeXchange.
- University of Zurich Switzerland
- ETH Zurich Switzerland
- Technical University of Munich Germany
- Thermo Fisher Scientific (United States) United States
- Thermo Fisher Scientific (Israel) Israel
Proteomics, Proteome, Genome, Human, Tandem Mass Spectrometry, Humans, Databases, Protein, Chromatography, Liquid
Proteomics, Proteome, Genome, Human, Tandem Mass Spectrometry, Humans, Databases, Protein, Chromatography, Liquid
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