Sulfonylurea treatment in a girl with neonatal diabetes (KCNJ11 R201H) and celiac disease: Impact of low compliance to the gluten free diet
Copyright policy )Sulfonylurea treatment in a girl with neonatal diabetes (KCNJ11 R201H) and celiac disease: Impact of low compliance to the gluten free diet
A girl with celiac disease and KCNJ11 mutation was transferred to glibenclamide when 19.8 years old. When her compliance to the gluten free diet worsened, her metabolic control deteriorated. Since glibenclamide is absorbed in the intestine, its absorption seems to be impaired by chronic malabsorption, increasing the risk of hyperglycaemia.
Potassium Channels, inwardly rectifying potassium channel subunit Kir6.2, Sulfonylurea, Gluten free diet, Glyburide, Celiac disease, Insulin, KCNJ11, gene mutation, glucose, juvenile diabetes mellitu, hemoglobin A1c, insulin derivative, adult, article, Diabetes Mellitu, Hemoglobin A, Autoantibodie, Inwardly Rectifying, Celiac disease; Gluten free diet; KCNJ11; Neonatal diabetes; Sulfonylurea, Sulfonylurea Compound, female, glibenclamide, Female, drug dose increase, Glycosylated, oral glucose tolerance test, patient compliance, Diet, Gluten-Free, Young Adult, Neonatal diabete, Diabetes Mellitus, case report, Humans, Hypoglycemic Agents, human, Potassium Channels, Inwardly Rectifying, insulin treatment, Autoantibodies, Glycated Hemoglobin, Transglutaminases, drug absorption, hemoglobin blood level, Hypoglycemic Agent, glibenclamide; glucose; hemoglobin A1c; insulin derivative; inwardly rectifying potassium channel subunit Kir6.2; sulfonylurea; adult; article; case report; celiac disease; drug absorption; drug dose increase; female; gene mutation; glucose blood level; gluten free diet; hemoglobin blood level; human; human tissue; hyperglycemia; insulin treatment; juvenile diabetes mellitus; oral glucose tolerance test; patient compliance; Amino Acid Substitution; Autoantibodies; Diabetes Mellitus; Diet, Gluten-Free; Female; Glyburide; Hemoglobin A, Glycosylated; Humans; Hypoglycemic Agents; Infant, Newborn; Insulin; Intestinal Absorption; Patient Compliance; Potassium Channels, Inwardly Rectifying; Sulfonylurea Compounds; Transglutaminases; Young Adult, Infant, Newborn, Infant, Newborn, Transglutaminase, human tissue, Diet, glucose blood level, Sulfonylurea Compounds, Amino Acid Substitution, Intestinal Absorption, Gluten-Free, Patient Compliance, hyperglycemia
Potassium Channels, inwardly rectifying potassium channel subunit Kir6.2, Sulfonylurea, Gluten free diet, Glyburide, Celiac disease, Insulin, KCNJ11, gene mutation, glucose, juvenile diabetes mellitu, hemoglobin A1c, insulin derivative, adult, article, Diabetes Mellitu, Hemoglobin A, Autoantibodie, Inwardly Rectifying, Celiac disease; Gluten free diet; KCNJ11; Neonatal diabetes; Sulfonylurea, Sulfonylurea Compound, female, glibenclamide, Female, drug dose increase, Glycosylated, oral glucose tolerance test, patient compliance, Diet, Gluten-Free, Young Adult, Neonatal diabete, Diabetes Mellitus, case report, Humans, Hypoglycemic Agents, human, Potassium Channels, Inwardly Rectifying, insulin treatment, Autoantibodies, Glycated Hemoglobin, Transglutaminases, drug absorption, hemoglobin blood level, Hypoglycemic Agent, glibenclamide; glucose; hemoglobin A1c; insulin derivative; inwardly rectifying potassium channel subunit Kir6.2; sulfonylurea; adult; article; case report; celiac disease; drug absorption; drug dose increase; female; gene mutation; glucose blood level; gluten free diet; hemoglobin blood level; human; human tissue; hyperglycemia; insulin treatment; juvenile diabetes mellitus; oral glucose tolerance test; patient compliance; Amino Acid Substitution; Autoantibodies; Diabetes Mellitus; Diet, Gluten-Free; Female; Glyburide; Hemoglobin A, Glycosylated; Humans; Hypoglycemic Agents; Infant, Newborn; Insulin; Intestinal Absorption; Patient Compliance; Potassium Channels, Inwardly Rectifying; Sulfonylurea Compounds; Transglutaminases; Young Adult, Infant, Newborn, Infant, Newborn, Transglutaminase, human tissue, Diet, glucose blood level, Sulfonylurea Compounds, Amino Acid Substitution, Intestinal Absorption, Gluten-Free, Patient Compliance, hyperglycemia
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